⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4479796 | 0.79 | — | — | |
| SCHEMBL1914283 | 0.78 | — | — | |
| SCHEMBL1914243 | 0.78 | — | — | |
| SCHEMBL29203369 | 0.76 | — | — | |
| SCHEMBL2542679 | 0.76 | — | — | |
| SCHEMBL25242370 | 0.76 | — | — | |
| SCHEMBL8513978 | 0.76 | — | — | |
| SCHEMBL25251818 | 0.74 | — | — | |
| SCHEMBL25243556 | 0.74 | — | — | |
| SCHEMBL25251585 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117597120-A | Spiroindolone compounds as Kv1.3 potassium Shaker channel blockers | D·E·萧尔研究有限责任公司 | 2024-02-23 | — | — | CN | disclosed |