Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 20/20 | 0.44 |
| ▸ | EED | O75530 | 1/20 | 0.44 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.44 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.44 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.44 |
| ▸ | EZH1 | Q92800 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21633557 | 1.00 | EZH2 (0.44) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL21689406 | 0.95 | EZH2 (0.45) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL21633535 | 0.88 | EZH2 (0.46) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL15731248 | 0.88 | EZH2 (0.46) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL30777390 | 0.88 | EZH2 (0.46) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL24072862 | 0.84 | EZH2 (0.47) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL13280413 | 0.84 | EZH2 (0.43) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL15700535 | 0.83 | EZH2 (0.47) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL21633810 | 0.83 | EZH2 (0.47) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL30777381 | 0.83 | EZH2 (0.47) | EZH2EEDRBBP4SUZ12AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250387402-A1 | POLYSUBSTITUTED BENZENE COMPOUND AND PREPARATION METHOD AND USE THEREOF | EVOPOINT BIOSCIENCES CO LTD (CN) | 2025-12-25 | — | — | US | disclosed |
| US-12390472-B2 | Polysubstituted benzene compound and preparation method and use thereof | Evopoint Biosciences Co., Ltd. (CN) | 2025-08-19 | — | — | US | disclosed |
| CN-113480525-B | Polysubstituted benzene ring compound, preparation method and application thereof | 苏州信诺维医药科技股份有限公司 | 2024-02-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250387402-A1 | POLYSUBSTITUTED BENZENE COMPOUND AND PREPARATION METHOD AND USE THEREOF | EZH2, BMI1, DOT1L | EZH2 1/4885EED 14/4885RBBP4 417/4885 |
| US-12390472-B2 | Polysubstituted benzene compound and preparation method and use thereof | EZH2, BMI1, SUZ12 | EZH2 1/4885EED 4/4885RBBP4 130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.