Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 17/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 15/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3077775 | 1.00 | CYP3A4 (0.76) | CYP3A4CYP2C19CYP2C9CYP2D6CYP1A2 | |
| SCHEMBL2902601 | 0.92 | CYP3A4 (0.68) | CYP3A4CYP2C19CYP2C9CYP2D6CYP1A2 | |
| SCHEMBL2902599 | 0.92 | CYP3A4 (0.68) | CYP3A4CYP2C19CYP2C9CYP2D6CYP1A2 | |
| SCHEMBL2906743 | 0.92 | CYP3A4 (0.69) | CYP3A4CYP2C19CYP2C9CYP2D6CYP1A2 | |
| SCHEMBL2906738 | 0.92 | CYP3A4 (0.69) | CYP3A4CYP2C19CYP2C9CYP2D6CYP1A2 | |
| SCHEMBL3084430 | 0.91 | CYP3A4 (0.75) | CYP3A4CYP2C19CYP2C9CYP2D6CYP1A2 | |
| SCHEMBL3084429 | 0.91 | CYP3A4 (0.75) | CYP3A4CYP2C19CYP2C9CYP2D6CYP1A2 | |
| SCHEMBL2906809 | 0.89 | CYP3A4 (0.64) | CYP3A4CYP2C19CYP2C9CYP2D6CYP1A2 | |
| SCHEMBL2906803 | 0.89 | CYP3A4 (0.64) | CYP3A4CYP2C19CYP2C9CYP2D6CYP1A2 | |
| SCHEMBL3077620 | 0.88 | CYP3A4 (0.63) | CYP3A4CYP2C19CYP2C9CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080261944-A1 | Indole Derivatives as Antiviral Agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2008-10-23 | — | — | US | claimed |
| US-7795250-B2 | Indole derivatives as antiviral agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2010-09-14 | — | — | US | disclosed |
| US-20080261944-A1 | Indole Derivatives as Antiviral Agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261944-A1 | Indole Derivatives as Antiviral Agents | IDO1, IDO2, IRF3 | CYP3A4 95/4885CYP2C19 469/4885CYP2C9 319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.