Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | PLK4 | O00444 | 1/20 | 0.30 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.30 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
| ▸ | PRKCG | P05129 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30778246 | 0.95 | MAPT (0.47) | MAPTNR1H2HSD11B1FFAR1KCNN4 | |
| SCHEMBL29159290 | 0.90 | MAPT (0.53) | MAPTFFAR1ALDH1A1TSHRMMP9 | |
| SCHEMBL30778220 | 0.86 | MAPT (0.43) | MAPTALDH1A1TSHRL3MBTL1HTT | |
| SCHEMBL30778250 | 0.86 | MAPT (0.47) | MAPTNR1H2FFAR1ALDH1A1TSHR | |
| SCHEMBL29159304 | 0.84 | MAPT (0.47) | MAPTNR1H2FFAR1ALDH1A1TSHR | |
| SCHEMBL29159293 | 0.82 | MAPT (0.39) | MAPTALDH1A1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL30778253 | 0.81 | MAPT (0.47) | MAPTMMP9NR1I2 | |
| SCHEMBL30778219 | 0.81 | MAPT (0.54) | MAPTNR1H2ALDH1A1MMP9SMN1; SMN2 | |
| SCHEMBL30778209 | 0.81 | MAPT (0.47) | MAPTNR1H2ALDH1A1TSHRMMP9 | |
| SCHEMBL30778204 | 0.81 | MAPT (0.35) | MAPTALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117603027-A | Olefin difunctional method and delta-trifluoromethyl ketone product prepared by same | 重庆理工大学 | 2024-02-27 | — | — | CN | disclosed |