Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30778243 | 0.94 | MAPT (0.44) | MAPTKIF11CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29159290 | 0.88 | MAPT (0.53) | MAPTCYP3A4CYP2C9CYP2C19FFAR1 | |
| SCHEMBL30778250 | 0.87 | MAPT (0.47) | MAPTKIF11FFAR1GRM5ALDH1A1 | |
| SCHEMBL30778255 | 0.82 | MAPT (0.45) | MAPTKIF11CYP3A4CYP2D6KCNH2 | |
| SCHEMBL30778219 | 0.82 | MAPT (0.54) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30778253 | 0.79 | MAPT (0.47) | MAPT | |
| SCHEMBL29159304 | 0.79 | MAPT (0.47) | MAPTKIF11FFAR1PTGESALDH1A1 | |
| SCHEMBL30778246 | 0.79 | MAPT (0.47) | MAPTFFAR1LMNAALDH1A1FFAR4 | |
| SCHEMBL30778220 | 0.79 | MAPT (0.43) | MAPTKIF11LMNAALDH1A1TSHR | |
| SCHEMBL30778256 | 0.79 | MAPT (0.50) | MAPTFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117603027-A | Olefin difunctional method and delta-trifluoromethyl ketone product prepared by same | 重庆理工大学 | 2024-02-27 | — | — | CN | disclosed |