Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 2/20 | 0.38 |
| ▸ | CLK3 | P49761 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | PRKCH | P24723 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24753673 | 1.00 | CYP11B1 (0.42) | CYP11B1CYP11B2CLK2CLK3DYRK1A | |
| SCHEMBL30059257 | 0.86 | FGFR2 (0.42) | KDM5AKDM4CKDM5BTTK | |
| SCHEMBL24753289 | 0.76 | AXL (0.34) | CHUKPRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL24753674 | 0.72 | CYP11B1 (0.35) | CYP11B1CYP11B2CLK2CLK3DYRK1A | |
| SCHEMBL30056998 | 0.72 | CYP11B1 (0.35) | CYP11B1CYP11B2CLK2CLK3DYRK1A | |
| SCHEMBL15036345 | 0.72 | CLK2 (0.40) | CYP11B1CYP11B2CLK2CLK3DYRK1A | |
| SCHEMBL24753558 | 0.71 | MAP4K1 (0.40) | — | |
| SCHEMBL1459164 | 0.70 | CYP19A1 (0.48) | CLK2CLK3DYRK1ACHUK | |
| SCHEMBL24754301 | 0.70 | — | — | |
| SCHEMBL24754324 | 0.70 | SYK (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117460732-A | Pyrrolopyridone compounds, preparation method and application thereof | 杭州中美华东制药有限公司 | 2024-01-26 | — | — | CN | disclosed |