SCHEMBL30782823

SCHEMBL30782823

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nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MME P08473 3/20 0.46
GNPAT O15228 1/20 0.46
TGFBR1 P36897 1/20 0.41
ENPEP Q07075 5/20 0.40
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
PDCD1LG2 Q9BQ51 1/20 0.40
CD274 Q9NZQ7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30886538 1.00 MME (0.46) MMEGNPATTGFBR1ENPEPCA2
SCHEMBL29591002 1.00 MME (0.46) MMEGNPATTGFBR1ENPEPCA2
SCHEMBL30881174 1.00 MME (0.46) MMEGNPATTGFBR1ENPEPCA2
SCHEMBL29630398 0.98 MME (0.47) MMEGNPATTGFBR1ENPEPCA2
SCHEMBL29503906 0.98 MME (0.47) MMEGNPATTGFBR1ENPEPCA2
SCHEMBL30193323 0.98 MME (0.47) MMEGNPATTGFBR1ENPEPCA2
SCHEMBL30099579 0.97 MME (0.50) MMEGNPATTGFBR1ENPEPPDCD1LG2
SCHEMBL29591607 0.97 MME (0.50) MMEGNPATTGFBR1ENPEPPDCD1LG2
SCHEMBL31064879 0.97 GNPAT (0.48) MMEGNPATTGFBR1ENPEPCA2
SCHEMBL29679876 0.95 MME (0.51) MMEGNPATTGFBR1ENPEPPDCD1LG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117695408-A Drug delivery nano-carrier and preparation method and application thereof 中国科学院深圳先进技术研究院 2024-03-15 CN claimed
EP-4673179-A1 BONE-DIRECTED THERAPEUTICS FOR THE TREATMENT OF CANCER William Marsh Rice University (US) 2026-01-07 EP disclosed
WO-2024254472-A1 OSTEOCLAST-DERIVED MICROVESICLES AND METHODS OF PROMOTING BONE REGENERATION THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) 2024-12-12 WO disclosed
CN-119055683-A Preparation method and application of osteoblast targeting engineering cow milk small extracellular vesicles 大连医科大学 2024-12-03 CN disclosed
WO-2024182454-A1 BONE-DIRECTED THERAPEUTICS FOR THE TREATMENT OF CANCER WILLIAM MARSH RICE UNIVERSITY (US) 2024-09-06 WO disclosed
CN-117695408-A Drug delivery nano-carrier and preparation method and application thereof 中国科学院深圳先进技术研究院 2024-03-15 CN disclosed