Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.58 |
| ▸ | MEN1 | O00255 | 11/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | CASP1 | P29466 | 2/20 | 0.55 |
| ▸ | CASP7 | P55210 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29169478 | 1.00 | MAPT (0.58) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL30782947 | 0.91 | MAPT (0.57) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL30782948 | 0.91 | MAPT (0.57) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29169443 | 0.91 | MAPT (0.57) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29169458 | 0.91 | MAPT (0.57) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29169444 | 0.88 | MEN1 (0.54) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL30782951 | 0.88 | MEN1 (0.54) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL30782949 | 0.88 | MEN1 (0.52) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29169451 | 0.88 | MEN1 (0.52) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL30782952 | 0.85 | MEN1 (0.69) | MAPTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117700389-B | Synthesis and anti-tumor activity research of novel coumarin structure-containing drug small molecules | 长春工业大学 | 2024-10-08 | — | — | CN | disclosed |
| CN-117700389-A | Synthesis and anti-tumor activity research of novel coumarin structure-containing drug small molecules | 长春工业大学 | 2024-03-15 | — | — | CN | disclosed |