Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | BRAF | P15056 | 2/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MDM4 | O15151 | 1/20 | 0.52 |
| ▸ | P4HB | P07237 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27379922 | 1.00 | MCL1 (0.65) | MCL1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL27379918 | 0.87 | MCL1 (0.57) | MCL1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL30783058 | 0.87 | MCL1 (0.57) | MCL1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9965507 | 0.85 | MCL1 (0.70) | MCL1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL30783048 | 0.85 | MCL1 (0.70) | MCL1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL27379925 | 0.85 | MCL1 (0.56) | MCL1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL30783042 | 0.85 | MCL1 (0.56) | MCL1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL27379916 | 0.80 | MCL1 (0.50) | MCL1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL30783052 | 0.80 | MCL1 (0.50) | MCL1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL23847653 | 0.79 | MCL1 (1.00) | MCL1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073624-A2 | ANTIPROLIFERATIVE BETTI BASES AND PRODRUGS THEREOF | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2024-04-04 | — | — | WO | disclosed |