Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TLR2 | O60603 | 3/20 | 0.49 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30783506 | 1.00 | KMT2A (0.49) | KMT2ATLR2TLR1MDM2NPSR1 | |
| SCHEMBL30783454 | 1.00 | KMT2A (0.49) | KMT2ATLR2TLR1MDM2NPSR1 | |
| SCHEMBL31298680 | 0.94 | KMT2A (0.50) | KMT2ATLR2TLR1MDM2NPSR1 | |
| SCHEMBL30783501 | 0.94 | KMT2A (0.50) | KMT2ATLR2TLR1MDM2NPSR1 | |
| SCHEMBL26241192 | 0.93 | TLR2 (0.53) | KMT2ATLR2TLR1MDM2NPSR1 | |
| SCHEMBL30783495 | 0.93 | TLR2 (0.54) | KMT2ATLR2TLR1MDM2NPSR1 | |
| SCHEMBL27261267 | 0.93 | TLR2 (0.54) | KMT2ATLR2TLR1MDM2NPSR1 | |
| SCHEMBL15706348 | 0.92 | TLR2 (0.54) | KMT2ATLR2TLR1MDM2NPSR1 | |
| SCHEMBL30783509 | 0.92 | TLR2 (0.54) | KMT2ATLR2TLR1MDM2NPSR1 | |
| SCHEMBL15706322 | 0.92 | TLR2 (0.54) | KMT2ATLR2TLR1MDM2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4561998-A1 | FIBROBLAST ACTIVATION PROTEIN-TARGETED COMPOSITIONS AND METHODS OF USE THEREOF | Ratio Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026072-A1 | FIBROBLAST ACTIVATION PROTEIN-TARGETED COMPOSITIONS AND METHODS OF USE THEREOF | RATIO THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |