Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | AKT2 | P31751 | 1/20 | 0.48 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.48 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | DRD4 | P21917 | 4/20 | 0.34 |
| ▸ | DRD3 | P35462 | 4/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30784478 | 0.90 | AKT1 (0.44) | AKT1AKT2AKT3CRHR1HTT | |
| SCHEMBL30784348 | 0.90 | AKT1 (0.47) | AKT1AKT2AKT3CRHR1KMT2A | |
| SCHEMBL30783721 | 0.90 | AKT1 (0.47) | AKT1AKT2AKT3CRHR1ALDH1A1 | |
| SCHEMBL30783583 | 0.90 | AKT1 (0.47) | AKT1AKT2AKT3CRHR1KMT2A | |
| SCHEMBL30721019 | 0.90 | AKT1 (0.47) | AKT1AKT2AKT3CRHR1ALDH1A1 | |
| SCHEMBL25361160 | 0.89 | AKT1 (0.48) | AKT1AKT2AKT3CRHR1ALDH1A1 | |
| SCHEMBL30495111 | 0.89 | AKT1 (0.48) | AKT1AKT2AKT3CRHR1ALDH1A1 | |
| SCHEMBL30494961 | 0.89 | AKT1 (0.50) | AKT1AKT2AKT3CRHR1ALDH1A1 | |
| SCHEMBL25359802 | 0.89 | AKT1 (0.50) | AKT1AKT2AKT3CRHR1ALDH1A1 | |
| SCHEMBL25360674 | 0.89 | AKT1 (0.52) | AKT1AKT2AKT3CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026424-A1 | QUINAZOLINONE DERIVATIVES AS AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |