Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 3/20 | 0.40 |
| ▸ | PIM1 | P11309 | 3/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | PDE9A | O76083 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30783587 | 0.85 | CDC7 (0.40) | TMIGD3ADORA1CDC7PIM1CSNK2B | |
| SCHEMBL30784315 | 0.82 | TMIGD3 (0.39) | TMIGD3ADORA1CDC7PIM1CSNK2B | |
| SCHEMBL30783861 | 0.75 | KMT2A (0.48) | TMIGD3CDC7PIM1PARP1HTT | |
| SCHEMBL22600573 | 0.75 | PARP14 (0.41) | TMIGD3ADORA1CDC7PIM1CSNK2B | |
| SCHEMBL30783662 | 0.74 | PDE1B (0.41) | PIK3CAPDE1C | |
| SCHEMBL30783874 | 0.71 | TMIGD3 (0.38) | TMIGD3ADORA1CDC7PIM1CSNK2B | |
| SCHEMBL25359756 | 0.71 | PARP1 (0.49) | PIM1PARP1PRNPPPARGHTT | |
| SCHEMBL30494981 | 0.71 | PARP1 (0.49) | PIM1PARP1PRNPPPARGHTT | |
| SCHEMBL30762450 | 0.71 | PRNP (0.34) | PRNPPPARGHTTNCOA2NPSR1 | |
| SCHEMBL30784410 | 0.70 | PIK3CA (0.40) | PRNPPPARGHTTNCOA2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026424-A1 | QUINAZOLINONE DERIVATIVES AS AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |