Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 4/20 | 0.34 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | CCR3 | P51677 | 4/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786061 | 0.83 | KDR (0.38) | MCHR1KDRKCNH2MCHR2CNR1 | |
| SCHEMBL31475241 | 0.82 | BDKRB1 (0.32) | — | |
| SCHEMBL31475185 | 0.81 | KDR (0.34) | MCHR1KDRKCNH2 | |
| SCHEMBL30786102 | 0.81 | CHEK1 (0.32) | — | |
| SCHEMBL31576782 | 0.78 | KDR (0.59) | MCHR1KDRCCR3 | |
| SCHEMBL31475212 | 0.78 | KDR (0.37) | KDRCNR1CNR2 | |
| SCHEMBL30786153 | 0.77 | KDR (0.36) | MCHR1KDRCCR3 | |
| SCHEMBL31475215 | 0.77 | KDR (0.37) | KDRCNR1CNR2 | |
| SCHEMBL31475221 | 0.76 | PRKCQ (0.34) | — | |
| SCHEMBL31475199 | 0.76 | KDR (0.34) | MCHR1KDRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119604488-A | Protein tyrosine kinase inhibitor and medical application thereof | 苏州必扬医药科技有限公司 | 2025-03-11 | — | — | CN | disclosed |
| WO-2024032584-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 苏州必扬医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |