SCHEMBL307863

SCHEMBL307863

Clc1cccc(-c2nc(-c3cccc(Cl)c3)nc(C(Cl)(Cl)Cl)n2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.46
NR1I3 Q14994 1/20 0.44
CYP19A1 P11511 1/20 0.43
IDH1 O75874 1/20 0.42
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GAA P10253 1/20 0.41
MPI P34949 1/20 0.41
GFER P55789 1/20 0.41
DPP4 P27487 2/20 0.41
HRH4 Q9H3N8 1/20 0.40
NPC1 O15118 3/20 0.40
RAB9A P51151 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TGFBR1 P36897 1/20 0.40
PDE4B Q07343 1/20 0.40
TSHR P16473 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
NOTUM Q6P988 1/20 0.40
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1048783 0.96 IDO1 (0.46) IDO1NR1I3CYP19A1IDH1KDM4E
SCHEMBL10589866 0.86 IDO1 (0.57) IDO1NR1I3CYP19A1IDH1KDM4E
SCHEMBL391621 0.83 IDH1 (0.46) IDO1NR1I3IDH1HRH4TGFBR1
SCHEMBL5574497 0.83 CYP19A1 (0.42) IDO1NR1I3CYP19A1KDM4EALDH1A1
SCHEMBL1049369 0.81 IDO1 (0.46) IDO1NR1I3CYP19A1IDH1KDM4E
SCHEMBL30035200 0.80 NR1I3 (0.57) IDO1NR1I3CYP19A1DPP4HRH4
SCHEMBL30476538 0.80 IDO1 (0.52) IDO1NR1I3CYP19A1IDH1KDM4E
SCHEMBL20150033 0.80 NR1I3 (0.57) IDO1NR1I3CYP19A1DPP4HRH4
SCHEMBL17416252 0.80 IDO1 (0.52) IDO1NR1I3CYP19A1IDH1KDM4E
SCHEMBL15477947 0.80 NR1I3 (0.57) IDO1NR1I3CYP19A1DPP4HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2154162-B1 REACTIVE URETHANE COMPOUND HAVING ETHER BOND, CURABLE COMPOSITION AND CURED MATERIAL SHOWA DENKO KK (JP) 2019-07-17 EP disclosed
EP-2356182-B1 RADIATION CURABLE COATING MATERIALS BASF SE (DE) 2015-05-06 EP disclosed
CN-102216400-B Radiation curable coating materials BASF SE 2013-12-18 CN disclosed
US-20130299736-A1 RADIATION-CURABLE COATING MATERIALS BASE SE (DE) 2013-11-14 US disclosed
US-8399569-B2 Reactive urethane compound having ether bond, curable composition, and cured material SHOWA DENKO K.K. (JP) 2013-03-19 US disclosed
EP-1866357-B1 (METH)ACRYLOYL GROUP-CONTAINING AROMATIC ISOCYANATE COMPOUND AND PRODUCTION PROCESS THEREOF SHOWA DENKO KK (JP) 2012-02-22 EP disclosed
US-8092982-B2 Photosensitive paste composition, barrier rib prepared using the composition and plasma display panel comprising the barrier rib SAMSUNG SDI CO., LTD. (KR) 2012-01-10 US disclosed
US-8044235-B2 (Meth) acryloyl group-containing aromatic isocyanate compound and production process thereof SHOWA DENKO K.K. (JP) 2011-10-25 US disclosed
US-20110230617-A1 RADIATION-CURABLE COATING MATERIALS BASF SE (DE) 2011-09-22 US disclosed
EP-2356182-A1 RADIATION CURABLE COATING MATERIALS BASF SE (DE) 2011-08-17 EP disclosed
EP-1820064-A2 RADIATION-CURABLE COATING SUBSTANCES BASF AKTIENGESELLSCHAFT (DE) 2007-08-22 EP disclosed
WO-2006058731-A2 RADIATION-CURABLE COATING SUBSTANCES BASF AKTIENGESELLSCHAFT (DE) 2006-06-08 WO disclosed
US-20040157140-A1 Photosensitive coloring composition, color filter using the composition and method of producing the same SHOWA DENKO K.K. (JP) 2004-08-12 US disclosed
EP-1002817-B1 Photocurable composition SHOWA DENKO KK (JP) 2004-04-28 EP disclosed
EP-0915136-B1 Photocurable paint composition for road markings SHOWA DENKO KK (JP) 2004-01-21 EP disclosed
US-6486225-B1 Photocurable composition SHOWA DENKO KABUSHIKI KAISHA (JP) 2002-11-26 US disclosed
US-6211260-B1 MARKING ROADS WITH CURABLE PAINT, FILLERS, GLASS BEADS, CATIONIC DYES AND QUATERNARY ORGANIC BORATES SHOWA DENKO K.K. (JP) 2001-04-03 US disclosed
US-6110987-A CURED PRODUCTS HAVING AN EXCELLENT APPEARANCE WITHOUT COLORING CAUSED BY POLYMERIZATION INITIATOR SHOWA DENKO K.K. (JP) 2000-08-29 US disclosed
EP-1002817-A2 Photocurable composition SHOWA DENKO KABUSHIKI KAISHA (JP) 2000-05-24 EP disclosed
EP-0915136-A1 Photocurable paint composition for road markings SHOWA DENKO KABUSHIKI KAISHA (JP) 1999-05-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110230617-A1 RADIATION-CURABLE COATING MATERIALS RAD51, MGMT, RAD54L IDO1 2355/4885NR1I3 1409/4885CYP19A1 2434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.