SCHEMBL30786353

SCHEMBL30786353

CC(C)[Si](O[C@@H]1CC[C@@H](c2cccc(F)c2F)[C@@H](N)c2cccnc21)(C(C)C)C(C)C

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CALCRL Q16602 11/20 0.48
ADRB2 P07550 1/20 0.48
CYP3A4 P08684 1/20 0.48
HTR1A P08908 5/20 0.36
SLC6A2 P23975 5/20 0.36
SLC6A4 P31645 5/20 0.36
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15674334 1.00 CALCRL (0.48) CALCRLADRB2CYP3A4HTR1ASLC6A2
SCHEMBL2521766 1.00 CALCRL (0.48) CALCRLADRB2CYP3A4HTR1ASLC6A2
SCHEMBL15674335 1.00 CALCRL (0.48) CALCRLADRB2CYP3A4HTR1ASLC6A2
SCHEMBL12537558 1.00 CALCRL (0.48) CALCRLADRB2CYP3A4HTR1ASLC6A2
SCHEMBL1670266 1.00 CALCRL (0.48) CALCRLADRB2CYP3A4HTR1ASLC6A2
Hydrochloric Acid SCHEMBL31530485 0.99 CALCRL (0.47) CALCRLADRB2CYP3A4HTR1ASLC6A2
SCHEMBL19183603 0.91 CALCRL (0.40) CALCRLADRB2CYP3A4HTR1ASLC6A2
SCHEMBL16616000 0.88 CALCRL (0.38) CALCRLADRB2CYP3A4HTR1ASLC6A2
SCHEMBL16615999 0.88 CALCRL (0.38) CALCRLADRB2CYP3A4HTR1ASLC6A2
SCHEMBL16624591 0.88 CALCRL (0.38) CALCRLADRB2CYP3A4HTR1ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117486798-B Crystal form of ramipam intermediate hydrochloride and preparation method thereof 南京威凯尔生物医药科技有限公司 2025-02-07 CN disclosed
CN-117486798-A Crystal form of ramipam intermediate hydrochloride and preparation method thereof 南京威凯尔生物医药科技有限公司 2024-02-02 CN disclosed