Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 8/20 | 0.62 |
| ▸ | MC5R | P33032 | 4/20 | 0.62 |
| ▸ | MC3R | P41968 | 4/20 | 0.62 |
| ▸ | MC1R | Q01726 | 4/20 | 0.62 |
| ▸ | TSLP | Q969D9 | 4/20 | 0.52 |
| ▸ | F12 | P00748 | 4/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.52 |
| ▸ | TUBB | P07437 | 1/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.52 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.52 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.52 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29615129 | 0.96 | MC4R (0.67) | MC4RMC5RMC3RMC1RF12 | |
| SCHEMBL29615119 | 0.96 | MC4R (0.67) | MC4RMC5RMC3RMC1RF12 | |
| SCHEMBL29615117 | 0.96 | MC4R (0.67) | MC4RMC5RMC3RMC1RF12 | |
| SCHEMBL30787032 | 0.94 | MC4R (0.65) | MC4RMC5RMC3RMC1RTSLP | |
| SCHEMBL30787033 | 0.93 | MC4R (0.63) | MC4RMC5RMC3RMC1RF12 | |
| SCHEMBL29615370 | 0.92 | MC4R (0.68) | MC4RMC5RMC3RMC1RF12 | |
| SCHEMBL29615196 | 0.91 | MC4R (0.73) | MC4RMC5RMC3RMC1RTSLP | |
| SCHEMBL29615197 | 0.91 | MC4R (0.73) | MC4RMC5RMC3RMC1RTSLP | |
| SCHEMBL29615288 | 0.90 | MC4R (0.60) | MC4RMC5RMC3RMC1RTSLP | |
| SCHEMBL29615038 | 0.90 | MC4R (0.60) | MC4RMC5RMC3RMC1RTSLP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618952-A2 | METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST | Rhythm Pharmaceuticals, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| CN-120152725-A | Methods of treating obesity using MC4R agonists | 节奏制药公司 | 2025-06-13 | — | — | CN | disclosed |
| WO-2025106751-A1 | COMBINATIONS OF A POTASSIUM CHANNEL ACTIVATOR AND AN MC4R AGONIST AND RELATED METHODS OF USE | RHYTHM PHARMACEUTICALS, INC. (US) | 2025-05-22 | — | — | WO | disclosed |
| EP-4554607-A2 | METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST | Rhythm Pharmaceuticals, Inc. (US) | 2025-05-21 | — | — | EP | disclosed |
| WO-2024108198-A2 | METHODS OF TREATING OBESITY WITH AN MC4R AGONIST | RHYTHM PHARMACEUTICALS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024015880-A2 | METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST | RHYTHM PHARMACEUTICALS, INC. (US) | 2024-01-18 | — | — | WO | disclosed |