Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 8/20 | 0.73 |
| ▸ | ECE1 | P42892 | 5/20 | 0.64 |
| ▸ | IL1RN | P18510 | 7/20 | 0.62 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.62 |
| ▸ | EDNRA | P25101 | 1/20 | 0.62 |
| ▸ | MMP2 | P08253 | 2/20 | 0.60 |
| ▸ | ACE | P12821 | 2/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | MMP1 | P03956 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32681291 | 0.92 | ERAP2 (0.68) | ERAP2ECE1IL1RNERAP1MMP2 | |
| SCHEMBL29492470 | 0.92 | ACE (0.62) | ERAP2ECE1MMP2ACEMMP9 | |
| SCHEMBL29380886 | 0.89 | ACE (0.73) | ERAP2ECE1ACE | |
| SCHEMBL21641791 | 0.89 | ACE (0.73) | ERAP2ECE1ACE | |
| SCHEMBL21641792 | 0.89 | ACE (0.73) | ERAP2ECE1ACE | |
| SCHEMBL21641793 | 0.89 | ACE (0.73) | ERAP2ECE1ACE | |
| SCHEMBL30051522 | 0.89 | ERAP2 (0.72) | ERAP2ECE1IL1RNERAP1ACE | |
| SCHEMBL31042842 | 0.88 | ERAP2 (0.69) | ERAP2ECE1IL1RNERAP1EDNRA | |
| SCHEMBL31337768 | 0.87 | ERAP2 (0.67) | ERAP2ECE1IL1RNERAP1EDNRA | |
| SCHEMBL31563651 | 0.87 | ERAP2 (0.67) | ERAP2ECE1IL1RNERAP1EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240042063-A1 | LINKED AND OTHER pH-TRIGGERED COMPOUNDS | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES | 2024-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240042063-A1 | LINKED AND OTHER pH-TRIGGERED COMPOUNDS | LIPA, PHOSPHO1, NGLY1 | ERAP2 735/4885ECE1 1676/4885IL1RN 3749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.