Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 4/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.32 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2123528 | 1.00 | GRM2 (0.64) | GRM2KCNH2XIAPBIRC2MLNR | |
| SCHEMBL30789127 | 0.89 | GRM2 (0.78) | GRM2KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL2123824 | 0.89 | GRM2 (0.78) | GRM2KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL15098092 | 0.87 | GRM2 (0.54) | GRM2KDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL13154730 | 0.86 | GRM2 (0.65) | GRM2KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL2123941 | 0.86 | GRM2 (0.47) | GRM2KCNH2KDM4EALDH1A1MAPK1 | |
| SCHEMBL2612606 | 0.83 | GRM2 (0.61) | GRM2KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL2612600 | 0.83 | GRM2 (0.61) | GRM2KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL30789126 | 0.83 | GRM2 (0.61) | GRM2KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL2122944 | 0.83 | GRM2 (0.61) | GRM2KCNH2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |
| WO-2024028611-A1 | OXADIAZOLE COMPOUNDS FOR USE IN THE TREATMENT OF OBSESSIVE COMPULSIVE DISORDER | SIRGARTAN HOLDINGS LTD (GB) | 2024-02-08 | — | — | WO | disclosed |