SCHEMBL30790691

SCHEMBL30790691

OBO.OBOC1=CCOCC1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17429089 0.98
SCHEMBL28402195 0.72
SCHEMBL12450251 0.71
SCHEMBL266354 0.70
SCHEMBL2258059 0.69 MAPK1 (0.32) MAPK1
SCHEMBL357991 0.67 MAPK1 (0.36) MAPK1
SCHEMBL18652826 0.66
SCHEMBL12512431 0.63 MAPK1 (0.33) MAPK1
SCHEMBL12496864 0.63 PIK3CD (0.34) MAPK1
SCHEMBL29042323 0.62 MAPK1 (0.30) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111741955-B DNA-PK inhibitors 沃泰克斯药物股份有限公司 2024-02-23 CN disclosed