Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 13/20 | 0.48 |
| ▸ | HTR2B | P41595 | 9/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 3/20 | 0.38 |
| ▸ | CD44 | P16070 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12878847 | 1.00 | POLB (0.51) | POLBSMN1; SMN2HTR2CHTR2BCYP3A4 | |
| Hydrochloric Acid SCHEMBL18550271 | 0.98 | POLB (0.50) | POLBSMN1; SMN2HTR2CHTR2BCYP3A4 | |
| Trifluoroacetic Acid SCHEMBL18550341 | 0.85 | HTR2C (0.41) | POLBSMN1; SMN2HTR2CHTR2BCYP3A4 | |
| SCHEMBL26640418 | 0.85 | HTR2C (0.55) | POLBSMN1; SMN2HTR2CHTR2BCHRM4 | |
| Hydrochloric Acid SCHEMBL26640478 | 0.84 | HTR2C (0.54) | POLBSMN1; SMN2HTR2CHTR2BCHRM4 | |
| SCHEMBL18818489 | 0.82 | HTR2C (0.37) | POLBSMN1; SMN2HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL21591718 | 0.81 | HTR2C (0.36) | POLBSMN1; SMN2HTR2CHTR2B | |
| SCHEMBL4135011 | 0.78 | POLB (0.51) | POLBSMN1; SMN2HTR2CHTR2BCYP3A4 | |
| SCHEMBL2449506 | 0.78 | POLB (0.51) | POLBSMN1; SMN2HTR2CHTR2BCYP3A4 | |
| SCHEMBL2183634 | 0.78 | POLB (0.51) | POLBSMN1; SMN2HTR2CHTR2BCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4572761-A1 | COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS | Mironid Limited (GB) | 2025-06-25 | — | — | EP | disclosed |
| CN-119730854-A | Compounds and their use as PDE4 activators | 米罗尼德有限公司 | 2025-03-28 | — | — | CN | disclosed |
| WO-2024038129-A1 | COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS | MIRONID LIMITED (GB) | 2024-02-22 | — | — | WO | disclosed |