Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 17/20 | 0.68 |
| ▸ | NTRK3 | Q16288 | 16/20 | 0.68 |
| ▸ | NTRK2 | Q16620 | 16/20 | 0.68 |
| ▸ | CSF1R | P07333 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29387482 | 1.00 | NTRK1 (0.68) | NTRK1NTRK3NTRK2CSF1RPDGFRB | |
| SCHEMBL28933431 | 0.89 | NTRK1 (0.71) | NTRK1NTRK3NTRK2CSF1RPDGFRB | |
| SCHEMBL28933432 | 0.89 | NTRK1 (0.71) | NTRK1NTRK3NTRK2CSF1RPDGFRB | |
| SCHEMBL28684876 | 0.87 | NTRK1 (0.68) | NTRK1NTRK3NTRK2CSF1RPDGFRB | |
| SCHEMBL28684874 | 0.87 | NTRK1 (0.68) | NTRK1NTRK3NTRK2CSF1RPDGFRB | |
| SCHEMBL28933421 | 0.86 | NTRK1 (0.72) | NTRK1NTRK3NTRK2CSF1RPDGFRB | |
| SCHEMBL28706603 | 0.86 | NTRK1 (0.72) | NTRK1NTRK3NTRK2CSF1RPDGFRB | |
| SCHEMBL28706602 | 0.86 | NTRK1 (0.72) | NTRK1NTRK3NTRK2CSF1RPDGFRB | |
| SCHEMBL28933419 | 0.86 | NTRK1 (0.72) | NTRK1NTRK3NTRK2CSF1RPDGFRB | |
| SCHEMBL29854882 | 0.85 | NTRK1 (0.77) | NTRK1NTRK3NTRK2CSF1RPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072387-B | Indazole compound, pharmaceutical composition and application thereof | 暨南大学 | 2024-03-08 | — | — | CN | disclosed |