Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK3 | Q16288 | 12/20 | 0.66 |
| ▸ | NTRK1 | P04629 | 11/20 | 0.66 |
| ▸ | NTRK2 | Q16620 | 11/20 | 0.66 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 4/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29855172 | 1.00 | NTRK3 (0.66) | NTRK3NTRK1NTRK2CHEK1KDR | |
| SCHEMBL28700923 | 0.82 | NTRK3 (0.70) | NTRK3NTRK1NTRK2CHEK1KDR | |
| SCHEMBL28700920 | 0.82 | NTRK3 (0.70) | NTRK3NTRK1NTRK2CHEK1KDR | |
| SCHEMBL28686120 | 0.80 | NTRK3 (0.66) | NTRK3NTRK1NTRK2CHEK1KDR | |
| SCHEMBL29854929 | 0.80 | NTRK1 (1.00) | NTRK3NTRK1NTRK2CHEK1KDR | |
| SCHEMBL28706602 | 0.80 | NTRK1 (0.72) | NTRK3NTRK1NTRK2CHEK1KDR | |
| SCHEMBL28933419 | 0.80 | NTRK1 (0.72) | NTRK3NTRK1NTRK2CHEK1KDR | |
| SCHEMBL28706603 | 0.80 | NTRK1 (0.72) | NTRK3NTRK1NTRK2CHEK1KDR | |
| SCHEMBL28686119 | 0.80 | NTRK3 (0.66) | NTRK3NTRK1NTRK2CHEK1KDR | |
| SCHEMBL28690940 | 0.80 | NTRK3 (1.00) | NTRK3NTRK1NTRK2CHEK1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072387-B | Indazole compound, pharmaceutical composition and application thereof | 暨南大学 | 2024-03-08 | — | — | CN | disclosed |