Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.61 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | RXRG | P48443 | 1/20 | 0.55 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 7/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | DHFR | P00374 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | AGXT | P21549 | 2/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792409 | 0.83 | MAOB (0.58) | MAOBALKBH1MAOANR4A2IDO1 | |
| SCHEMBL29442816 | 0.83 | MAOB (0.62) | MAOBRXRARXRBRXRGALKBH1 | |
| SCHEMBL21384055 | 0.83 | MAOB (0.62) | MAOBRXRARXRBRXRGALKBH1 | |
| SCHEMBL457443 | 0.82 | P4HTM (0.53) | MAOBALKBH1MAOANR4A2 | |
| SCHEMBL11959143 | 0.80 | MAOB (0.72) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL15111000 | 0.79 | MAOB (0.66) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL11377856 | 0.79 | MAOB (0.56) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL30792252 | 0.78 | MAOB (0.56) | MAOBALKBH1MAOANR4A2DHFR | |
| SCHEMBL30792322 | 0.78 | MAOB (0.50) | MAOBALKBH1MAOA | |
| SCHEMBL3624161 | 0.77 | MAOB (0.73) | MAOBRXRARXRBRXRGMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658885-A | Benzyloxy aryl compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-03-08 | — | — | CN | disclosed |