Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792335 | 0.86 | MAOB (0.48) | MAOBMAOACYP4F2CYP4A11 | |
| SCHEMBL30792322 | 0.84 | MAOB (0.50) | MAOBMAOAHDAC1HDAC6HDAC5 | |
| SCHEMBL2142663 | 0.83 | PDGFRB (0.47) | MAOBMAOAHDAC6ALOX5 | |
| SCHEMBL30792390 | 0.82 | MAOB (0.54) | MAOBMAOA | |
| SCHEMBL20361166 | 0.75 | HTR2C (0.41) | MAOBMAOAPPARA | |
| SCHEMBL30792336 | 0.75 | MAOB (0.51) | MAOBMAOAHDAC1HDAC6HDAC5 | |
| SCHEMBL16047663 | 0.75 | MAOB (0.45) | MAOBMAOAHDAC1HDAC6HDAC5 | |
| SCHEMBL16047069 | 0.74 | MAOB (0.44) | MAOBMAOAACHEMAPK14CYP4F2 | |
| SCHEMBL16046736 | 0.74 | MAOB (0.47) | MAOBMAOAACHECYP4F2CYP4A11 | |
| SCHEMBL28597894 | 0.73 | MAOB (0.47) | MAOBMAOACYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658885-A | Benzyloxy aryl compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-03-08 | — | — | CN | disclosed |