Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30793973 | 0.83 | — | — | |
| SCHEMBL30793843 | 0.81 | — | — | |
| SCHEMBL30793892 | 0.81 | — | — | |
| SCHEMBL30793253 | 0.79 | — | — | |
| SCHEMBL30793352 | 0.79 | HTR2A (0.32) | — | |
| SCHEMBL25339293 | 0.76 | CXCR4 (0.34) | CXCR4 | |
| SCHEMBL31057579 | 0.74 | GLP1R (0.32) | CXCR4 | |
| SCHEMBL26686886 | 0.73 | CXCR4 (0.38) | CXCR4 | |
| SCHEMBL31057594 | 0.71 | CXCR4 (0.36) | CXCR4 | |
| SCHEMBL30793737 | 0.71 | PDE4A (0.39) | CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4540254-A1 | TETRAHYDROPYRIDOPYRIMIDINE PAN-KRAS INHIBITORS | Mirati Therapeutics, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023244604-A1 | TETRAHYDROPYRIDOPYRIMIDINE PAN-KRAS INHIBITORS | Mirati Therapeutics, Inc. (US) | 2023-12-21 | — | — | WO | disclosed |