Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 20/20 | 0.77 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4537146 | 1.00 | GRM5 (0.77) | GRM5PGRKCNH2 | |
| SCHEMBL4543610 | 1.00 | GRM5 (0.77) | GRM5PGRKCNH2 | |
| SCHEMBL4543623 | 0.95 | GRM5 (0.85) | GRM5PGRKCNH2 | |
| SCHEMBL4559952 | 0.95 | GRM5 (0.85) | GRM5PGRKCNH2 | |
| SCHEMBL4538693 | 0.95 | GRM5 (0.69) | GRM5PGRKCNH2 | |
| SCHEMBL13640407 | 0.95 | GRM5 (0.69) | GRM5PGRKCNH2 | |
| SCHEMBL4537773 | 0.92 | GRM5 (0.72) | GRM5PGRKCNH2 | |
| SCHEMBL30796545 | 0.92 | GRM5 (0.72) | GRM5PGRKCNH2 | |
| SCHEMBL4534268 | 0.92 | GRM5 (0.72) | GRM5PGRKCNH2 | |
| SCHEMBL4542477 | 0.90 | GRM5 (0.69) | GRM5PGRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |