SCHEMBL30794659

SCHEMBL30794659

Cc1ccc(Oc2ccc(-c3ccn4c(CC(F)(F)F)nnc4c3Cl)cc2F)c(C)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 20/20 1.00
KCNH2 Q12809 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL739896 1.00 GRM2 (1.00) GRM2KCNH2
SCHEMBL743859 0.92 GRM2 (0.85) GRM2KCNH2
SCHEMBL742941 0.86 GRM2 (1.00) GRM2KCNH2
SCHEMBL740635 0.86 GRM2 (1.00) GRM2KCNH2
SCHEMBL30795978 0.84 GRM2 (0.76) GRM2KCNH2
SCHEMBL739577 0.84 GRM2 (0.76) GRM2KCNH2
SCHEMBL744799 0.78 GRM2 (1.00) GRM2
SCHEMBL7857919 0.77 GRM2 (1.00) GRM2
SCHEMBL738010 0.77 GRM2 (0.83) GRM2KCNH2
SCHEMBL741592 0.76 GRM2 (1.00) GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4584250-A1 COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS Biohaven Therapeutics Ltd. (VG) 2025-07-16 EP disclosed
WO-2024054811-A1 COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS BIOHAVEN THERAPEUTICS LTD. (VG) 2024-03-14 WO disclosed