Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | MAP2 | P11137 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | RPA1 | P27694 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3091466 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1HPGDMAP2GAA | |
| Hydrochloric Acid SCHEMBL5203951 | 0.79 | KDM4E (0.96) | KDM4EALDH1A1HPGDMAP2GAA | |
| SCHEMBL40526 | 0.77 | KDM4E (0.69) | KDM4EALDH1A1HPGDMAP2GAA | |
| SCHEMBL7591935 | 0.77 | KDM4E (0.79) | KDM4EALDH1A1HPGDMAP2GAA | |
| SCHEMBL9441674 | 0.74 | KDM4E (0.79) | KDM4EALDH1A1HPGDMAP2GAA | |
| SCHEMBL9816507 | 0.74 | KDM4E (0.79) | KDM4EALDH1A1HPGDMAP2GAA | |
| SCHEMBL7594894 | 0.72 | KDM4E (0.71) | KDM4EALDH1A1HPGDMAP2GAA | |
| SCHEMBL19133601 | 0.71 | KDM4E (0.74) | KDM4EALDH1A1HPGDMAP2GAA | |
| SCHEMBL31013209 | 0.71 | KDM4E (0.64) | KDM4EALDH1A1HPGDMAP2GAA | |
| SCHEMBL18919796 | 0.71 | KDM4E (0.64) | KDM4EALDH1A1HPGDMAP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117677606-A | 2-carboxy-indole inhibitors of metallo-beta-lactamase | 牛津大学创新有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-117677606-A | 2-carboxy-indole inhibitors of metallo-beta-lactamase | 牛津大学创新有限公司 | 2024-03-08 | — | — | CN | disclosed |