Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.55 |
| ▸ | PRCP | P42785 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.52 |
| ▸ | CLPP | Q16740 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL600601 | 1.00 | GRM5 (0.55) | GRM5PRCPNPC1MAPK1RAB9A | |
| SCHEMBL599756 | 0.88 | GRM5 (0.53) | GRM5CLPPMEN1KMT2AHCRTR1 | |
| SCHEMBL600363 | 0.86 | GRM5 (0.68) | GRM5MAPK1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL193610 | 0.84 | GRM5 (0.73) | GRM5NPC1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL193609 | 0.84 | GRM5 (0.73) | GRM5NPC1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL599528 | 0.80 | GRM5 (0.50) | GRM5SMN1; SMN2ALDH1A1CLPPMEN1 | |
| SCHEMBL7879774 | 0.77 | GRM5 (0.49) | GRM5CLPPMEN1KMT2AATM | |
| SCHEMBL599414 | 0.77 | GRM5 (0.49) | GRM5CLPPMEN1KMT2AATM | |
| SCHEMBL4143678 | 0.75 | MEN1 (0.74) | GRM5RAB9ASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL4143674 | 0.75 | MEN1 (0.74) | GRM5RAB9ASMN1; SMN2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |