SCHEMBL3079488

SCHEMBL3079488

Cc1cc2cc(O)c(O)cc2oc1=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B3 P37058 1/20 0.62
PON1 P27169 1/20 0.58
AKR1B1 P15121 3/20 0.50
HPGD P15428 3/20 0.50
KDM4E B2RXH2 3/20 0.50
CYP3A4 P08684 3/20 0.50
ALDH1A1 P00352 2/20 0.50
MCL1 Q07820 2/20 0.50
HSD17B10 Q99714 2/20 0.50
XDH P47989 2/20 0.50
MAPT P10636 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
CA12 O43570 1/20 0.50
LMNA P02545 1/20 0.50
CYP1A2 P05177 1/20 0.50
BCHE P06276 1/20 0.50
GLA P06280 1/20 0.50
GAA P10253 1/20 0.50
ALOX15 P16050 1/20 0.50
ACHE P22303 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27454187 0.98 HSD17B3 (0.61) HSD17B3PON1AKR1B1HPGDKDM4E
Dimethylamine SCHEMBL27470490 0.94 HSD17B3 (0.57) HSD17B3PON1AKR1B1HPGDKDM4E
Dimethylamine SCHEMBL27455945 0.93 HSD17B3 (0.56) HSD17B3PON1AKR1B1HPGDKDM4E
Acetic Acid SCHEMBL1983488 0.90 HSD17B3 (0.53) HSD17B3PON1AKR1B1HPGDKDM4E
SCHEMBL17942935 0.85 HSD17B3 (0.56) HSD17B3PON1AKR1B1HPGDKDM4E
SCHEMBL15842923 0.83 HSD17B3 (0.60) HSD17B3PON1HPGDALDH1A1HSD17B10
SCHEMBL2791740 0.83 AKR1B1 (0.61) HSD17B3PON1AKR1B1HPGDKDM4E
SCHEMBL16015217 0.83 KDM4E (0.60) HSD17B3PON1AKR1B1HPGDKDM4E
SCHEMBL126040 0.77 HSD17B3 (1.00) HSD17B3AKR1B1HPGDKDM4EALDH1A1
SCHEMBL10791744 0.77 HSD17B3 (0.74) HSD17B3HPGDKDM4EALDH1A1MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 226 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116589440-B Synthesis method of methyl esculetin sodium acetate 峰成医药科技(天津)有限公司 2023-09-19 CN claimed
CN-116589440-A Synthesis method of methyl esculetin sodium acetate 峰成医药科技(天津)有限公司 2023-08-15 CN claimed
CN-102245643-A Cosmetic composition containing acetylated oligoglucuronans SEDERMA SA 2011-11-16 CN claimed
CN-119606945-B Application of 4-methyl esculetin as potential active ingredient of XIASANGJU in preparation of medicine for preventing and treating diabetes 广州白云山星群(药业)股份有限公司 2025-05-06 CN disclosed
CN-119606945-A Application of 4-methyl esculetin as potential active ingredient of XIASANGJU in preparation of medicine for preventing and treating diabetes 广州白云山星群(药业)股份有限公司 2025-03-14 CN disclosed
CN-119562802-A Collagen compositions and methods of use thereof HTL生物创新股份有限公司 2025-03-04 CN disclosed
CN-116981440-A Oral care compositions 联合利华知识产权控股有限公司 2023-10-31 CN disclosed
CN-116589440-B Synthesis method of methyl esculetin sodium acetate 峰成医药科技(天津)有限公司 2023-09-19 CN disclosed
CN-116589440-B Synthesis method of methyl esculetin sodium acetate 峰成医药科技(天津)有限公司 2023-09-19 CN disclosed
CN-116589440-B Synthesis method of methyl esculetin sodium acetate 峰成医药科技(天津)有限公司 2023-09-19 CN disclosed
CN-116589440-A Synthesis method of methyl esculetin sodium acetate 峰成医药科技(天津)有限公司 2023-08-15 CN disclosed
CN-1145584-A Methods of using cyclicpolyanionic polyol derivatives for regulating skin wrinkles PROCTER & GAMBLE (US) 1997-03-19 CN disclosed
CN-1130381-A Use of coumarins and carbostyrils as PLAZ inhibitors, new coumarins and carbostyrils, process for prep, the same and medicaments BOEHERINGER MANNHEIM GMBH (DE) 1996-09-04 CN disclosed
CN-1074909-A UVA-absorbing sunscreen metal complexes RICHARDSON VICKS INC (US) 1993-08-04 CN disclosed
CN-1073858-A The preparation method of uva-absorbing sunscreen metal complexes RICHARDSON VICKS INC (US) 1993-07-07 CN disclosed
CN-1073859-A Regulate the compositions of wrinkle of skin and/or atrophoderma RICHARDSON VICKS INC (US) 1993-07-07 CN disclosed
CN-1072842-A The application aspect adjusting wrinkle of skin and/or atrophoderma of N-acetyl-L-cysteine and derivant thereof ONE PROCTER & GAMBLE PLAZA CIN (US) 1993-06-09 CN disclosed
CN-1068034-A Method with lysophosphatidic acids for regulating skin wrinkles PROCTER & GAMBLE (US) 1993-01-20 CN disclosed
CN-1066182-A Make human skin obtain a kind of artificial brown's stable emulsion composition RICHARDSON VICKS INC (US) 1992-11-18 CN disclosed
CN-1063038-A Retain in facial emulsion compositions RICHARDSON VICKS INC (US) 1992-07-29 CN disclosed