Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.56 |
| ▸ | CLPP | Q16740 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3586318 | 1.00 | GRM5 (0.56) | GRM5CLPPATML3MBTL1HSD11B1 | |
| SCHEMBL3586314 | 1.00 | GRM5 (0.56) | GRM5CLPPATML3MBTL1HSD11B1 | |
| SCHEMBL3591534 | 0.90 | PDE2A (0.49) | GRM5CLPPL3MBTL1HSD11B1NAMPT | |
| SCHEMBL3591531 | 0.90 | PDE2A (0.49) | GRM5CLPPL3MBTL1HSD11B1NAMPT | |
| SCHEMBL3585860 | 0.88 | GRM5 (0.58) | GRM5CLPPATML3MBTL1HSD11B1 | |
| SCHEMBL3585856 | 0.88 | GRM5 (0.58) | GRM5CLPPATML3MBTL1HSD11B1 | |
| SCHEMBL3584326 | 0.86 | GRM5 (0.58) | GRM5CLPPATML3MBTL1HSD11B1 | |
| SCHEMBL30794762 | 0.86 | GRM5 (0.58) | GRM5CLPPATML3MBTL1HSD11B1 | |
| SCHEMBL3584320 | 0.86 | GRM5 (0.58) | GRM5CLPPATML3MBTL1HSD11B1 | |
| SCHEMBL3584728 | 0.86 | GRM5 (0.68) | GRM5CLPPATML3MBTL1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |