Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.57 |
| ▸ | CLPP | Q16740 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3585711 | 1.00 | GRM5 (0.57) | GRM5CLPPMEN1KMT2AATM | |
| SCHEMBL3585701 | 1.00 | GRM5 (0.57) | GRM5CLPPMEN1KMT2AATM | |
| SCHEMBL30794762 | 0.91 | GRM5 (0.58) | GRM5CLPPMEN1KMT2AATM | |
| SCHEMBL3584320 | 0.91 | GRM5 (0.58) | GRM5CLPPMEN1KMT2AATM | |
| SCHEMBL3584326 | 0.91 | GRM5 (0.58) | GRM5CLPPMEN1KMT2AATM | |
| SCHEMBL3575099 | 0.91 | MEN1 (0.47) | GRM5CLPPMEN1KMT2AATM | |
| SCHEMBL3575094 | 0.91 | MEN1 (0.47) | GRM5CLPPMEN1KMT2AATM | |
| SCHEMBL30794419 | 0.91 | MEN1 (0.47) | GRM5CLPPMEN1KMT2AATM | |
| SCHEMBL3597100 | 0.90 | MEN1 (0.48) | GRM5CLPPMEN1KMT2AATM | |
| SCHEMBL3597096 | 0.90 | MEN1 (0.48) | GRM5CLPPMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |