Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4537802 | 1.00 | GRM5 (0.67) | GRM5 | |
| SCHEMBL4539792 | 0.88 | GRM5 (0.72) | GRM5 | |
| SCHEMBL4539399 | 0.86 | GRM5 (0.67) | GRM5 | |
| SCHEMBL4536781 | 0.86 | GRM5 (0.69) | GRM5 | |
| SCHEMBL30795734 | 0.86 | GRM5 (0.69) | GRM5 | |
| SCHEMBL4539243 | 0.86 | GRM5 (0.66) | GRM5 | |
| SCHEMBL4539624 | 0.85 | GRM5 (0.70) | GRM5 | |
| SCHEMBL4540797 | 0.85 | GRM5 (0.65) | GRM5 | |
| SCHEMBL5021631 | 0.84 | GRM5 (0.56) | GRM5 | |
| SCHEMBL4537098 | 0.84 | GRM5 (0.68) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |