SCHEMBL30795192

SCHEMBL30795192

Cc1cc(N2CCc3ccccc3C2)cc(Cl)c1NC(=O)CC(C)(C)C

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KCNQ2 O43526 19/20 0.67
KCNQ3 O43525 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1054657 1.00 KCNQ2 (0.67) KCNQ2KCNQ3L3MBTL1
SCHEMBL30795547 0.93 KCNQ2 (0.77) KCNQ2KCNQ3
SCHEMBL1078477 0.93 KCNQ2 (0.77) KCNQ2KCNQ3
SCHEMBL12926928 0.90 KCNQ2 (0.71) KCNQ2KCNQ3L3MBTL1
SCHEMBL30795894 0.90 KCNQ2 (0.71) KCNQ2KCNQ3
SCHEMBL1000993 0.90 KCNQ2 (0.71) KCNQ2KCNQ3
SCHEMBL30814177 0.88 KCNQ2 (0.87) KCNQ2KCNQ3
SCHEMBL1003007 0.88 KCNQ2 (0.87) KCNQ2KCNQ3
SCHEMBL1001954 0.88 KCNQ2 (0.80) KCNQ2KCNQ3
SCHEMBL30794663 0.88 KCNQ2 (0.80) KCNQ2KCNQ3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4584250-A1 COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS Biohaven Therapeutics Ltd. (VG) 2025-07-16 EP disclosed
EP-4580679-A1 COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS Biohaven Therapeutics Ltd. (VG) 2025-07-09 EP disclosed
WO-2024054811-A1 COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS BIOHAVEN THERAPEUTICS LTD. (VG) 2024-03-14 WO disclosed
WO-2024054807-A1 COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND TDP-43 MODULATORS BIOHAVEN THERAPEUTICS LTD. (VG) 2024-03-14 WO disclosed
WO-2024050389-A1 COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS BIOHAVEN THERAPEUTICS LTD. (VG) 2024-03-07 WO disclosed