Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR1B | P36896 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 5/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21310765 | 1.00 | ACVR1B (0.46) | ACVR1BTGFBR1PIM1PIM3PIM2 | |
| SCHEMBL24316789 | 0.80 | FYN (0.54) | ACVR1BTGFBR1PIM1PIM3PIM2 | |
| SCHEMBL29539345 | 0.80 | FYN (0.54) | ACVR1BTGFBR1PIM1PIM3PIM2 | |
| SCHEMBL11983571 | 0.79 | CCR1 (0.55) | ACVR1BTGFBR1PIM1PIM3PIM2 | |
| SCHEMBL19925989 | 0.78 | CYP11B1 (0.49) | PIM1MAPTKDM5BERN1FGFR3 | |
| SCHEMBL31375150 | 0.78 | CCNC (0.58) | ACVR1BTGFBR1PIM1PIM3PIM2 | |
| SCHEMBL16561177 | 0.76 | MKNK1 (0.51) | ACVR1BTGFBR1PIM1PIM3PIM2 | |
| SCHEMBL20074520 | 0.76 | AXL (0.51) | ACVR1BTGFBR1PIM1PIM3PIM2 | |
| SCHEMBL23119645 | 0.76 | FGFR3 (0.58) | ACVR1BTGFBR1PIM1PIM3PIM2 | |
| SCHEMBL18397077 | 0.76 | PIM1 (0.52) | ACVR1BTGFBR1PIM1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |