Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GPR183 | P32249 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.44 |
| ▸ | AKT1 | P31749 | 2/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2435168 | 1.00 | MAPT (0.57) | MAPTRAB9AGPR183P2RX7LMNA | |
| SCHEMBL2435553 | 0.91 | GPR183 (0.56) | MAPTRAB9AGPR183P2RX7LMNA | |
| SCHEMBL2434669 | 0.88 | MAPT (0.54) | MAPTRAB9ALMNAMAPK1AKT1 | |
| SCHEMBL30795907 | 0.88 | MAPT (0.54) | MAPTRAB9ALMNAMAPK1AKT1 | |
| SCHEMBL2432710 | 0.85 | GPR183 (0.50) | MAPTGPR183P2RX7LMNAEPHX2 | |
| SCHEMBL30795263 | 0.85 | GPR183 (0.50) | MAPTGPR183P2RX7LMNAEPHX2 | |
| SCHEMBL2434583 | 0.81 | GPR183 (0.71) | MAPTRAB9AGPR183P2RX7LMNA | |
| SCHEMBL2439725 | 0.80 | SMN1; SMN2 (0.52) | MAPTRAB9AGPR183LMNAEPHX2 | |
| SCHEMBL30814215 | 0.80 | MAPT (0.55) | MAPTRAB9ALMNAMAPK1KCNQ2 | |
| SCHEMBL2437088 | 0.80 | MAPT (0.55) | MAPTRAB9ALMNAMAPK1KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| EP-4580679-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS | Biohaven Therapeutics Ltd. (VG) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |
| WO-2024054807-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND TDP-43 MODULATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |
| WO-2024050389-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-07 | — | — | WO | disclosed |