Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 5/20 | 0.52 |
| ▸ | KCNQ3 | O43525 | 4/20 | 0.52 |
| ▸ | KCNQ4 | P56696 | 4/20 | 0.52 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3104145 | 1.00 | KCNQ2 (0.52) | KCNQ2KCNQ3KCNQ4KCNQ5MAPT | |
| SCHEMBL30795300 | 0.89 | KCNQ3 (0.53) | KCNQ2KCNQ3KCNQ4KCNQ5MAPT | |
| SCHEMBL3109017 | 0.89 | KCNQ3 (0.53) | KCNQ2KCNQ3KCNQ4KCNQ5MAPT | |
| SCHEMBL3104491 | 0.83 | KCNQ2 (0.52) | KCNQ2KCNQ3KCNQ4KCNQ5MAPT | |
| SCHEMBL30796603 | 0.82 | KCNQ3 (0.61) | KCNQ2KCNQ3KCNQ4KCNQ5MAPT | |
| SCHEMBL3089723 | 0.82 | KCNQ3 (0.61) | KCNQ2KCNQ3KCNQ4KCNQ5MAPT | |
| SCHEMBL3107615 | 0.80 | KCNQ2 (0.59) | KCNQ2KCNQ3KCNQ4KCNQ5MAPT | |
| SCHEMBL30795962 | 0.80 | KCNQ2 (0.74) | KCNQ2KCNQ3KCNQ4KCNQ5MAPT | |
| SCHEMBL30794470 | 0.80 | KCNQ2 (0.59) | KCNQ2KCNQ3KCNQ4KCNQ5MAPT | |
| SCHEMBL3106791 | 0.80 | KCNQ2 (0.74) | KCNQ2KCNQ3KCNQ4KCNQ5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| EP-4580679-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS | Biohaven Therapeutics Ltd. (VG) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |
| WO-2024054807-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND TDP-43 MODULATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |
| WO-2024050389-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-07 | — | — | WO | disclosed |