SCHEMBL30795804

SCHEMBL30795804

CC(C)(C)CC(=O)Nc1c(Cl)cc(N2CCc3ccccc3C2)cc1C(F)(F)F

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KCNQ2 O43526 19/20 0.57
KCNQ3 O43525 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1001090 1.00 KCNQ2 (0.57) KCNQ2KCNQ3
SCHEMBL14846478 0.91 KCNQ2 (0.61) KCNQ2KCNQ3
SCHEMBL30814196 0.90 KCNQ2 (0.60) KCNQ2KCNQ3
SCHEMBL1000859 0.90 KCNQ2 (0.60) KCNQ2KCNQ3
SCHEMBL12926913 0.90 KCNQ2 (0.62) KCNQ2KCNQ3
SCHEMBL1000192 0.90 KCNQ2 (0.73) KCNQ2KCNQ3
SCHEMBL30814264 0.90 KCNQ2 (0.59) KCNQ2KCNQ3
SCHEMBL30795009 0.90 KCNQ2 (0.67) KCNQ2KCNQ3
SCHEMBL1000323 0.90 KCNQ2 (0.67) KCNQ2KCNQ3
SCHEMBL1000265 0.90 KCNQ2 (0.59) KCNQ2KCNQ3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4584250-A1 COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS Biohaven Therapeutics Ltd. (VG) 2025-07-16 EP disclosed
EP-4580679-A1 COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS Biohaven Therapeutics Ltd. (VG) 2025-07-09 EP disclosed
WO-2024054811-A1 COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS BIOHAVEN THERAPEUTICS LTD. (VG) 2024-03-14 WO disclosed
WO-2024054807-A1 COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND TDP-43 MODULATORS BIOHAVEN THERAPEUTICS LTD. (VG) 2024-03-14 WO disclosed
WO-2024050389-A1 COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS BIOHAVEN THERAPEUTICS LTD. (VG) 2024-03-07 WO disclosed