SCHEMBL30795993

SCHEMBL30795993

COc1cc(C)ccc1C(=O)N1C[C@@H](c2noc(-c3cc(Cl)c[nH]3)n2)CC[C@H]1C

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HCRTR2 O43614 20/20 0.44
HCRTR1 O43613 19/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL600350 1.00 HCRTR2 (0.44) HCRTR2HCRTR1
SCHEMBL600760 0.91 HCRTR2 (0.48) HCRTR2HCRTR1
SCHEMBL601067 0.90 HCRTR2 (0.45) HCRTR2HCRTR1
SCHEMBL601712 0.87 HCRTR2 (0.46) HCRTR2HCRTR1
SCHEMBL599412 0.83 HCRTR2 (0.53) HCRTR2HCRTR1
SCHEMBL599312 0.83 HCRTR2 (0.64) HCRTR2HCRTR1
SCHEMBL599241 0.83 HCRTR1 (0.65) HCRTR2HCRTR1
SCHEMBL601121 0.83 HCRTR1 (0.44) HCRTR2HCRTR1
SCHEMBL600595 0.83 HCRTR1 (0.40) HCRTR2HCRTR1
SCHEMBL600589 0.82 PROKR1 (0.44) HCRTR2HCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4584250-A1 COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS Biohaven Therapeutics Ltd. (VG) 2025-07-16 EP disclosed
WO-2024054811-A1 COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS BIOHAVEN THERAPEUTICS LTD. (VG) 2024-03-14 WO disclosed