SCHEMBL30799482

SCHEMBL30799482

COc1c(Br)cncc1N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 1/20 0.32
MTNR1A P48039 1/20 0.32
MTNR1B P49286 1/20 0.32
AAK1 Q2M2I8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22885615 0.82 SSTR4 (0.33) SSTR4
SCHEMBL29843420 0.79 SSTR4 (0.34) SSTR4
SCHEMBL20517822 0.79 SSTR4 (0.34) SSTR4
SCHEMBL22636519 0.76 SSTR4 (0.32) SSTR4
SCHEMBL30799358 0.75 SSTR4 (0.33) SSTR4MTNR1AMTNR1B
SCHEMBL27079090 0.74 SSTR4 (0.35) SSTR4
SCHEMBL30823595 0.74 SSTR4 (0.35) SSTR4
SCHEMBL28759406 0.73 HSD17B10 (0.36) SSTR4MTNR1AMTNR1BAAK1
SCHEMBL20525185 0.73 SSTR4 (0.32) SSTR4
SCHEMBL23144008 0.72 CA12 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114853730-B Compounds used as HPK1 kinase inhibitor, preparation method and application thereof 中国药科大学 2024-03-26 CN disclosed