Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2066984 | 0.87 | AAK1 (0.37) | AAK1BACE1SOS1SSTR4USP30 | |
| SCHEMBL21332162 | 0.84 | BACE1 (0.38) | AAK1BACE1SOS1SSTR4USP30 | |
| SCHEMBL2067004 | 0.83 | AAK1 (0.38) | AAK1BACE1SSTR4LCKHSD17B10 | |
| SCHEMBL28549753 | 0.83 | BACE1 (0.38) | AAK1BACE1SSTR4USP30PDPK1 | |
| SCHEMBL26693647 | 0.82 | BACE1 (0.35) | AAK1BACE1SOS1SSTR4USP30 | |
| SCHEMBL29705323 | 0.82 | BACE1 (0.35) | AAK1BACE1SOS1SSTR4USP30 | |
| SCHEMBL30581085 | 0.81 | AAK1 (0.35) | AAK1BACE1SYK | |
| SCHEMBL30581083 | 0.81 | AAK1 (0.35) | AAK1BACE1SYK | |
| SCHEMBL31287082 | 0.79 | MAPT (0.35) | AAK1HSD17B10KDM4E | |
| SCHEMBL31287086 | 0.79 | MAPT (0.35) | AAK1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853730-B | Compounds used as HPK1 kinase inhibitor, preparation method and application thereof | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |