Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 6/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 3/20 | 0.36 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25937200 | 1.00 | KDM1A (0.42) | KDM1AMAOBBTKPIK3CDKMT2A | |
| SCHEMBL25937197 | 0.92 | PIK3CD (0.40) | KDM1AMAOBBTKPIK3CDKMT2A | |
| SCHEMBL30101652 | 0.92 | PIK3CD (0.40) | KDM1AMAOBBTKPIK3CDKMT2A | |
| SCHEMBL25937203 | 0.91 | PIK3CD (0.40) | KDM1AMAOBBTKPIK3CDKMT2A | |
| SCHEMBL30101675 | 0.91 | PIK3CD (0.40) | KDM1AMAOBBTKPIK3CDKMT2A | |
| SCHEMBL25937198 | 0.83 | PIK3CD (0.40) | KDM1AMAOBBTKPIK3CDKMT2A | |
| SCHEMBL30101648 | 0.83 | PIK3CD (0.40) | KDM1AMAOBBTKPIK3CDKMT2A | |
| SCHEMBL25938752 | 0.81 | PIK3CD (0.43) | KDM1AMAOBBTKPIK3CDKMT2A | |
| SCHEMBL30101627 | 0.80 | PIK3CD (0.40) | KDM1AMAOBBTKPIK3CDKMT2A | |
| SCHEMBL25938869 | 0.80 | PIK3CD (0.40) | KDM1AMAOBBTKPIK3CDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715905-A | Checkpoint kinase 1 (CHK 1) inhibitors and uses thereof | 无界生物公司 | 2024-03-15 | — | — | CN | disclosed |