Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29390905 | 1.00 | ESR2 (0.59) | ESR2NR1H2MAPTLMNAALDH1A1 | |
| SCHEMBL27087855 | 1.00 | ESR2 (0.59) | ESR2NR1H2MAPTLMNAALDH1A1 | |
| SCHEMBL4170697 | 1.00 | ESR2 (0.59) | ESR2NR1H2MAPTLMNAALDH1A1 | |
| SCHEMBL30184058 | 0.87 | ESR2 (0.60) | ESR2NR1H2MAPTLMNAALDH1A1 | |
| SCHEMBL28380071 | 0.87 | ESR2 (0.60) | ESR2NR1H2MAPTLMNAALDH1A1 | |
| SCHEMBL18875033 | 0.87 | ESR2 (0.57) | ESR2NR1H2MAPTLMNAALDH1A1 | |
| SCHEMBL18875037 | 0.87 | ESR2 (0.57) | ESR2NR1H2MAPTLMNAALDH1A1 | |
| SCHEMBL30875704 | 0.87 | ESR2 (0.60) | ESR2NR1H2MAPTLMNAALDH1A1 | |
| SCHEMBL31335703 | 0.86 | ESR2 (0.56) | ESR2NR1H2MAPTLMNAALDH1A1 | |
| SCHEMBL29557441 | 0.86 | ESR2 (0.56) | ESR2NR1H2MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545751-A | 2, 4-diaminopyrimidine derivatives as ULK1/2 inhibitors and their use | 生命爱科 | 2024-02-09 | — | — | CN | disclosed |