Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.45 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23326155 | 1.00 | HTR2A (0.53) | HTR2APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL23214857 | 0.80 | PDE4B (0.50) | HTR2APDE4BSCN9AALDH1A1KDM4E | |
| SCHEMBL29886238 | 0.80 | PDE4B (0.50) | HTR2APDE4BSCN9AALDH1A1KDM4E | |
| SCHEMBL28782624 | 0.79 | PDE4B (0.48) | HTR2APDE4BSCN9AALDH1A1MEN1 | |
| SCHEMBL23348062 | 0.78 | HTR2A (0.50) | HTR2APDE4BSCN9AALDH1A1MEN1 | |
| SCHEMBL28782629 | 0.77 | PDE4B (0.54) | PDE4BSCN9AALDH1A1MEN1KMT2A | |
| SCHEMBL23326161 | 0.73 | HTR2A (0.56) | HTR2APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL25277797 | 0.72 | PDE4B (0.48) | PDE4BSCN9APROKR1JAK2JAK1 | |
| SCHEMBL23326298 | 0.71 | PDE4B (0.61) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL29775437 | 0.71 | PDE4B (0.61) | PDE4BPDE4APDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761083-B | 5-HT for treating depression 2A Agonists | 罗福拉公司 | 2024-02-13 | — | — | CN | disclosed |