Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 20/20 | 0.51 |
| ▸ | IL2 | P60568 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29207788 | 0.91 | ITK (0.52) | ITKIL2 | |
| SCHEMBL24671478 | 0.91 | ITK (0.52) | ITKIL2 | |
| SCHEMBL30066383 | 0.91 | ITK (0.52) | ITKIL2 | |
| SCHEMBL24671735 | 0.91 | ITK (0.51) | ITKIL2 | |
| SCHEMBL30066413 | 0.90 | ITK (0.48) | ITKIL2 | |
| SCHEMBL29207820 | 0.90 | ITK (0.48) | ITKIL2 | |
| SCHEMBL24670152 | 0.90 | ITK (0.48) | ITKIL2 | |
| SCHEMBL30066596 | 0.79 | ITK (0.47) | ITKIL2 | |
| SCHEMBL24670081 | 0.79 | ITK (0.69) | ITKIL2 | |
| SCHEMBL13559070 | 0.78 | ITK (0.70) | ITKIL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693502-A | Compounds for inhibiting or degrading ITK, compositions comprising the same, methods of making the same, and methods of using the same | 纽力克斯治疗公司 | 2024-03-12 | — | — | CN | disclosed |