Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.44 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 5/20 | 0.36 |
| ▸ | NMT2 | O60551 | 4/20 | 0.36 |
| ▸ | QRFPR | Q96P65 | 2/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29355102 | 1.00 | PTGS1 (0.44) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL29375029 | 0.97 | PTGS1 (0.43) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL29475226 | 0.97 | PTGS1 (0.43) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL30662067 | 0.97 | PTGS1 (0.43) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL29509632 | 0.97 | PTGS1 (0.43) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL31018946 | 0.97 | PTGS1 (0.43) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL29350894 | 0.97 | PTGS1 (0.47) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL30923419 | 0.95 | PTGS1 (0.43) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL29356041 | 0.95 | PTGS1 (0.43) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL29360266 | 0.95 | PTGS1 (0.43) | PTGS1GSTK1GLO1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568699-A2 | RABIES G PROTEIN AND USES THEREOF | Icosavax, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| US-20250177513-A1 | RABIES G PROTEIN AND USES THEREOF | ICOSAVAX, INC. | 2025-06-05 | — | — | US | disclosed |
| CN-119836300-A | Rabies virus G protein and application thereof | Icosavax股份有限公司 | 2025-04-15 | — | — | CN | disclosed |
| WO-2024036193-A2 | RABIES G PROTEIN AND USES THEREOF | ICOSAVAX, INC. (US) | 2024-02-15 | — | — | WO | disclosed |