SCHEMBL30801636

SCHEMBL30801636

Cn1c(C2CC2)nc(-c2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)c1-c1cccnc1

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 6/20 0.48
IKZF2 Q9UKS7 11/20 0.47
IKZF1 Q13422 3/20 0.45
CSNK1A1 P48729 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27216934 1.00 CRBN (0.48) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL30801605 0.95 IKZF2 (0.47) CRBNIKZF2IKZF1
SCHEMBL30801573 0.95 IKZF2 (0.47) CRBNIKZF2IKZF1
SCHEMBL27217177 0.95 IKZF2 (0.47) CRBNIKZF2IKZF1
SCHEMBL27216958 0.91 CRBN (0.50) CRBNIKZF2IKZF1
SCHEMBL27217158 0.91 CRBN (0.53) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL27217350 0.90 CRBN (0.51) CRBNIKZF2IKZF1
SCHEMBL27217161 0.88 CRBN (0.51) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL27217267 0.87 IKZF2 (0.50) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL27217176 0.87 CRBN (0.49) CRBNIKZF2IKZF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4584259-A1 CK1ALPHA AND DUAL CK1ALPHA / GSPT1 DEGRADING COMPOUNDS Innovo Therapeutics, Inc. (US) 2025-07-16 EP disclosed
WO-2024054832-A1 CK1α AND DUAL CK1α / GSPT1 DEGRADING COMPOUNDS INNOVO THERAPEUTICS, INC. (US) 2024-03-14 WO disclosed