SCHEMBL30801641

SCHEMBL30801641

O=C1CCC(N2Cc3cc(-n4ccc(-c5ccccc5)n4)ccc3C2=O)C(=O)N1

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 9/20 0.57
CSNK1A1 P48729 1/20 0.54
IKZF2 Q9UKS7 7/20 0.51
IKZF1 Q13422 3/20 0.51
MAP1LC3B Q9GZQ8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27217017 1.00 CRBN (0.57) CRBNCSNK1A1IKZF2IKZF1MAP1LC3B
SCHEMBL27217031 0.91 CRBN (0.57) CRBNCSNK1A1IKZF2IKZF1MAP1LC3B
SCHEMBL30801594 0.83 CRBN (0.57) CRBNCSNK1A1IKZF2IKZF1
SCHEMBL27216991 0.83 CRBN (0.57) CRBNCSNK1A1IKZF2IKZF1
SCHEMBL27216982 0.83 CRBN (0.54) CRBNCSNK1A1IKZF2IKZF1
SCHEMBL31546782 0.82 IKZF2 (0.49) CRBNCSNK1A1IKZF2IKZF1
SCHEMBL27217314 0.81 CRBN (0.57) CRBNCSNK1A1IKZF2IKZF1
SCHEMBL25123250 0.81 CRBN (0.71) CRBNCSNK1A1IKZF2IKZF1MAP1LC3B
SCHEMBL27310844 0.80 CRBN (0.56) CRBNCSNK1A1IKZF2IKZF1
SCHEMBL25213181 0.79 CRBN (0.61) CRBNCSNK1A1IKZF2IKZF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4584259-A1 CK1ALPHA AND DUAL CK1ALPHA / GSPT1 DEGRADING COMPOUNDS Innovo Therapeutics, Inc. (US) 2025-07-16 EP disclosed
WO-2024054832-A1 CK1α AND DUAL CK1α / GSPT1 DEGRADING COMPOUNDS INNOVO THERAPEUTICS, INC. (US) 2024-03-14 WO disclosed