Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.53 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801734 | 0.90 | GRIN2B (0.66) | GRIN2BGRIN2CUSP30TSHRALOX15 | |
| SCHEMBL27336110 | 0.87 | GRIN2B (0.50) | GRIN2BGRIN2CUSP30TSHRALOX15 | |
| SCHEMBL27329709 | 0.84 | GRIN2B (0.44) | GRIN2BGRIN2CUSP30TSHRALOX15 | |
| SCHEMBL24339457 | 0.83 | GRIN2B (0.61) | GRIN2BGRIN2CUSP30TSHRALOX15 | |
| SCHEMBL30801674 | 0.82 | GRIN2B (0.37) | GRIN2BGRIN2CMMP2MMP13MMP14 | |
| SCHEMBL30801667 | 0.82 | USP30 (0.43) | GRIN2BGRIN2CUSP30TSHRALOX15 | |
| SCHEMBL27330073 | 0.82 | USP30 (0.48) | GRIN2BGRIN2CUSP30TSHRALOX15 | |
| SCHEMBL27330081 | 0.82 | USP30 (0.48) | GRIN2BGRIN2CUSP30TSHRALOX15 | |
| SCHEMBL27330087 | 0.82 | USP30 (0.48) | GRIN2BGRIN2CUSP30TSHRALOX15 | |
| SCHEMBL3497329 | 0.80 | USP30 (0.47) | GRIN2BGRIN2CUSP30TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054919-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (CN) | 2024-03-14 | — | — | WO | disclosed |