Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | YAP1 | P46937 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27336109 | 0.90 | USP30 (0.45) | USP30MEN1KMT2AMAPTGPR119 | |
| SCHEMBL28838755 | 0.86 | USP30 (0.47) | USP30MEN1KMT2AMAPTGPR119 | |
| SCHEMBL29053811 | 0.86 | USP30 (0.47) | USP30MEN1KMT2AMAPTGPR119 | |
| SCHEMBL23342653 | 0.86 | USP30 (0.47) | USP30MEN1KMT2AMAPTGPR119 | |
| SCHEMBL23342654 | 0.86 | USP30 (0.47) | USP30MEN1KMT2AMAPTGPR119 | |
| SCHEMBL23342651 | 0.86 | USP30 (0.47) | USP30MEN1KMT2AMAPTGPR119 | |
| SCHEMBL28838753 | 0.86 | USP30 (0.47) | USP30MEN1KMT2AMAPTGPR119 | |
| SCHEMBL20293883 | 0.83 | GRIN2B (0.57) | MEN1KMT2AMAPTGRIN2BGRIN2C | |
| SCHEMBL17352433 | 0.83 | GRIN2B (0.57) | MEN1KMT2AMAPTGRIN2BGRIN2C | |
| SCHEMBL19627469 | 0.83 | GRIN2B (0.57) | MEN1KMT2AMAPTGRIN2BGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054919-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (CN) | 2024-03-14 | — | — | WO | disclosed |